Monday, November 27, 2006

CO Bioscience Discovery Grant: $2,129,000

The State of Colorado Bioscience Discovery Grant Program provides matching funds for proof-of-concept projects. The University Colorado Tech Transfer Office selected 13 finalists from a large pool of applicants. The proposals totaled $2,129,000, and have been sent to the state for final review. Though funds are earmarked for technology that has not yet been obligated to an entity it will be exciting to watch the data that pours in and see if any start-ups emerge downstream as a direct correlation of this grant program.

Finalists included:

  • Stephen Hunsucker, School of Medicine, Department of Pediatrics, UCDHSC. “Protein Biomarkers to Differentially Diagnose Follicular Thyroid Carcinoma and Follicular Thyroid Adenoma.”
  • Leland Shapiro, School of Medicine, Division of Infectious Diseases, UCDHSC. “Infusion of Alpha-1-Antitrypsin (AAT) to Suppress Human Immunodeficiency Virus Type 1 (HIV) Replication in Patients.”
  • Steven Anderson, School of Medicine, Department of Pathology, UCDHSC. “Suppression of Irradiation-Induced Salivary Gland Dysfunction by IGF-1.”
  • Jeffrey Holt, School of Medicine, Department of Pathology, UCDHSC. “Biomarker Enabled Development of PARP Inhibitors for Cancer Therapy.”
  • Gary Brodsky, School of Medicine, Division of Medical Oncology, UCDHSC. “In-vivo Analysis of a Cardiac and Skeletal Muscle Stem Cell Activator.”
  • Edward Dempsey, School of Medicine, Cardiovascular Pulmonary Research Laboratory, UCDHSC. “Moving Bryostatin-1 from the Lab to the Clinic for the Treatment of Pulmonary Hypertension.”
  • Robert Hodges, School of Medicine, Department of Biochemistry and Molecular Genetics, UCDHSC. “Applicability of SARS Coronavirus Antibody Technology to Influenza Virus.”
  • Karen Stevens, School of Medicine, Department of Psychiatry, UCDHSC. “A New Treatment for Ineffectively Treated Schizophrenia Patients: Pre-clinical Validation for Centrally Administered Clozapine.”
  • Douglas Graham, School of Medicine, Department of Pediatrics, Center for Cancer and Blood Disorders, UCDHSC. “A Novel Biologically Targeted Agent for the Treatment of Non-Small Cell Lung Cancer.”
  • David Ross, School of Pharmacy, Department of Pharmaceutical Sciences, UCDHSC. “Hydroquinone Ansamycin Pro-drugs as Novel Anticancer Hsp90 Inhibitors.”
  • Tad Koch, Chemistry and Biochemistry, CU-Boulder. “New Targeted Drug for the Treatment of Lung Cancer.”
  • Christopher Bowman, Chemical and Biochemical Engineering, CU-Boulder. “Redox-Initiated Radical Chain Polymerization for the Detection and Amplification of Biological Recognition Events.”
  • Michael Larson, Mechanical Engineering, UCCS. “A Device for Laser Fusion of Septal Tissue.”


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Statistics give us more and more pieces of information that are bound to worry us, to make us react and change something if we can. More and more people and in earlier and earlier stages of their life die of a heart disease. Statistics, only in the US, are extremely alarming:
- Every 30 seconds someone dies because of a heart disease;
- More than 2.500 Americans die daily because of heart diseases;
- Every 20 seconds there is a person dying from a heart attack;
- Each year 6 million people are hospitalized because of a heart disease;
- The number 1 killer is a heart disease.
Although AEDs are not a universal panacea for all heart diseases, nothing else can compete to its major feature, that of actually re-starting the heart after it has been stopped by a sudden cardiac arrest. Under these circumstances is it necessary to ask you why anyone in this world, any family, in any home would hope for having such a device in their first aid locker?

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