Back in February CLSDF highlighted Quark Pharmaceuticals as another private company headquartered outside of Colorado yet with a major presence in Colorado. The company announced the close of a $27M financing led by SBI Asset Management which may enable drug candidates in five clinical programs by 2H08. As a result of the financing clinical operations in the Boulder office is expected to ramp. It already appears as though hiring in the office is underway (here) with more expected. Great news for Quark, for Boulder and for the continued advancement of siRNA technologies.
Quark has a robust product portfolio including two clinical, one pre-IND and six pre-clinical candidates in development. Its lead product candidates are RTP801i-14, an siRNA molecule in Phase I/IIa clinical trial for the treatment of wet age-related macular degeneration that is licensed to Pfizer on an exclusive worldwide basis. AKIi-5, a Phase I, siRNA molecule for the prevention of acute kidney injury and acute renal failure following major cardiac surgery, and AHLi-11, a pre-IND siRNA molecule for the prevention of chemotherapy and noise-induced hearing loss.
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